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Relaxed phylogenetics and dating with

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In this work, we propose a general bench mark of alternative relaxed clock models.

Relaxed molecular clock models allow divergence time dating and "relaxed phylogenetic" inference, in which a time tree is estimated in the face of unequal rates across lineages.

Each branch in a phylogeny (subtending a clade) is a possible location for a change of rate from one local clock to a new one.

Thus, including both the global molecular clock and the unconstrained model results, there are a total of 2 We propose an efficient method to sample this model space while simultaneously estimating the phylogeny.

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Contact:[email protected] Supplementary information: Estimating evolutionary timescales is a common aim of molecular phylogenetic analysis.